ON THE RELATIONSHIP OF TRADITIONAL AND NON-TRADITIONAL LIPID PARAMETERS WITH THE RISK OF PREDIABETES AND TYPE 2 DIABETES MELLITUS IN PATIENTS WITH CORONARY HEART DISEASE IN THE UZBEK POPULATION

Narimova G. J.; Kulimova G. A.

Authors

Narimova G. J.
Kulimova G. A. Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after Academician E.Kh. Turakulov, Khorezm Regional Endocrinology Dispensary, Diabetology Department Republic of Uzbekistan, 100125, Tashkent, st. Mirzo Ulugbek 56

Keywords:

Type 2 diabetes mellitus, coronary heart disease, correlation.

Abstract

The aim of this study was to compare the TG/HDL relationship andother non-traditional lipid parameters with pre-DM and T2DM in the Uzbek population of patients with coronary heart disease, and to test the association of high TG/HDL levels based on gender-specific thresholds with pre-DM and T2DM.
Material and methods of research.We studied the age characteristics of the surveyed rural population of Tuprok-Kal district in the Khorezm region. There were 132 women and 107 men. Of the 239 individuals, 100 patients with carbohydrate metabolism disorders and type 2 diabetes were identified. Among the 100 individuals with identified carbohydrate metabolism disorders, 46 patients with coronary heart disease were identified.
The following methods were used in the population survey: epidemiological, clinical, biochemical, instrumental and statistical.
Study results. Significant differences were observed in a number of parameters compared to the group without NMD. Significant differences were found in family history of type 2 diabetes, systolic blood pressure, diastolic blood pressure, smoking, alcohol abuse, and hypertension compared to all studied patient groups (p < 0.005). Patients with IFG+IGT and type 2 diabetes demonstrated the highest significance of differences in family history of type 2 diabetes, p < 0.0001.
Regarding biochemical parameters, it was revealed that the reliability of differences in the lipid spectrum was detected in patients with type 2 diabetes (p < 0.005), while in the other groups such differences were not detected.